Table 5.
Clinical Utility of Indium 111–Labeled White Blood Cell Scans by Clinical Indication, Scan Result, and Final Diagnosis
| Factor | Total | Overall Utilitya, No. (%) |
Definite Contributiona, No. (%) |
Possible Contributiona, No. (%) |
|---|---|---|---|---|
| All cases | 132 | 63 (48) | 56 (42) | 7 (5) |
| Reason for scan | ||||
| Osteomyelitis | 50 | 35 (70) | 30 (60) | 5 (10) |
| FUO | 35 | 12 (34) | 11 (31) | 1 (3) |
| Other known infection | 28 | 4 (14) | 3 (11) | 1 (4) |
| Vascular graft infection | 15 | 10 (67) | 10 (67) | … |
| Prosthetic device infection | 3 | 1 (33) | 1 (33) | … |
| Other | 1 | 1 (100) | 1 (100) | … |
| Scan result | ||||
| Positive | 41 | 24 (59) | 17 (41) | 7 (17) |
| Negative | 91 | 39 (43) | 39 (43) | … |
| Final diagnosis | ||||
| Infection | 83 | 30 (36) | 24 (29) | 6 (7) |
| Noninfectious | 31 | 26 (84) | 25 (81) | 1 (3) |
| Indeterminate | 18 | 7 (39) | 7 | … |
Abbreviations: FUO, fever of unknown origin.
a Utility determined by review of medical record by 2 independent reviewers as follows: overall utility—scans definitely or possibly contributed to the clinical management of the patient; definite contribution—scans were felt to definitely impact subsequent clinical management; possible contribution—scans may have impacted clinical management but other tests provided the same or similar information.