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. 2014 Aug 2;1(2):ofu049. doi: 10.1093/ofid/ofu049

Table 2.

Six-Month Rates of Persistent Post-Zoster Pain by Diabetes and Concomitant Immune-Compromised Status, 2005–2009

Herpes Zoster Cases
% Herpes Zoster Cases With Persistent Post-Zoster Pain
Diabetic Individuals
Nondiabetic Individuals
Diabetic Individuals
Nondiabetic Individuals
Difference
N N % 95% Confidence Interval [CI] % 95% CI P Value*
Total study population
 Enrollees in group 44 460 264 397 5.97 (5.75–6.19) 3.93 (3.86–4.01) <.01
 Sex
  Females 25 569 165 776 6.12 (5.83–6.42) 4.07 (3.98–4.17) <.01
  Males 18 891 98 621 5.77 (5.44–6.11) 3.69 (3.57–3.81) <.01
 Age group
  18–49 years 7685 111 980 3.55 (3.16–3.99) 1.85 (1.77–1.93) <.01
  50–59 years 15 125 78 084 4.70 (4.38–5.05) 3.60 (3.47–3.73) <.01
  60–64 years 8862 32 200 5.26 (4.81–5.74) 4.69 (4.47–4.93) .03
  ≥65 years 12 788 42 133 9.42 (8.92–9.93) 9.50 (9.22–9.78) .80
Immune competent
 Enrollees in group 40 998 247 371 5.84 (5.62–6.08) 3.77 (3.70–3.85) <.01
 Sex
  Females 23 582 154 677 6.06 (5.76–6.37) 3.94 (3.85–4.04) <.01
  Males 17 416 92 694 5.55 (5.22–5.90) 3.49 (3.37–3.61) <.01
 Age group
  18–49 years 7203 107 475 3.49 (3.09–3.93) 1.79 (1.71–1.87) <.01
  50–59 years 14 069 73 031 4.56 (4.23–4.92) 3.49 (3.36–3.62) <.01
  60–64 years 8155 29 507 5.15 (4.69–5.65) 4.65 (4.41–4.89) .07
  ≥65 years 11 571 37 358 9.36 (8.84–9.90) 9.34 (9.05–9.64) .94
Immune compromised
 Enrollees in group 3462 17 026 7.46 (6.63–8.38) 6.25 (5.89–6.62) <.01
 Sex
  Females 1987 11 099 6.85 (5.82–8.04) 5.91 (5.49–6.37) .09
  Males 1475 5927 8.28 (6.98–9.79) 6.87 (6.26–7.54) .05
 Age group
  18–49 years 482 4505 4.56 (3.03–6.80) 3.31 (2.83–3.87) .15
  50–59 years 1056 5053 6.55 (5.20–8.20) 5.17 (4.59–5.81) .06
  60–64 years 707 2693 6.52 (4.92–8.58) 5.20 (4.42–6.10) .14
  ≥65 years 1217 4775 9.94 (8.38–11.75) 10.75 (9.90–11.66) .43

* P value for the difference between the risks was based on Fisher's exact test.