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. 2014 Nov 6;125(1):199–205. doi: 10.1182/blood-2014-06-584789

Table 2.

Univariate analysis of factors potentially associated with grade III-IV aGVHD in 106 DCBT recipients

Variable N Day 180 grade III-IV aGVHD, % (95% CI) P
Age, y
 0-15 14 21 (5-46) .921
 ≥16 92 21 (13-30)
Conditioning
 Myeloablative 80 20 (12-29) .764
 Nonmyeloablative 26 23 (9-41)
Infused total CD3+ cell dose
 ≤7.74 × 106/kg 55 26 (15-38) .170
 >7.74 × 106/kg 51 16 (7-27)
Dominant unit-recipient 6 allele HLA match
 Worse HLA match: 2-3/6 28 32 (16-50) .077
 Better HLA match: 4-6/6 78 17 (9-26)
ST2 level, ng/mL
 Low: ≤33.9 56 13 (5-23) .024
 High: >33.9 50 30% (18-43)