Survival and molecular features of ColSBE. (A) Survival curves based on ColSBE as classified by the LDA equation using standardized Ct values for those cases with survival data available. (B) Survival curves for patients harboring or not the mutation in IDH1. In each plot, the amount of cases per group is shown as well as its associated p value, which indicates the probability that curves are equal, the death hazard ratio (HR) computed from the Cox's proportional hazard model is depicted, as well as the p value providing the probability that the HR is different than zero. (C) The histograms summarize the molecular features based on MGMT expression and IDH1 mutational status (codon 132). The left-side bars describe the percentage of cases within each ColSBE group below the MGMT average expression, while the right-side bars provide the percentage of cases showing IDH1 mutation in each ColSBE group. The GHE/GLE indicates the fold-change between groups for the MGMT expression levels. The p value denotes the probability that proportions are equal.