Table 2.
Changes in the Levels of Inflammatory Mediators in Mouse Plasma Between High-Fat Diet and Sesame Oil Diet Groups
| Relative protein levels compared to ATH, fold difference | ||||
|---|---|---|---|---|
| Protein name | Symbol | ATH/HF diet | Sesame oil diet | P values |
| Downregulated | ||||
| Tyrosine protein kinase | Axl | 1 | 0.548 | *.018 |
| B-lymphocyte chemoattractant | BLC | 1 | 0.759 | *.036 |
| Eotaxin | Eotaxin | 1 | 0.871 | .69 |
| Eotaxin2 | Eotaxin-2 | 1 | 0.818 | .167 |
| TNF superfamily, member 6 | FAS ligand | 1 | 0.975 | .909 |
| Fractalkine | Fractalkine | 1 | 0.886 | .19 |
| Granulocyte macrophage colony-stimulating factor | GM-CSF | 1 | 0.823 | .618 |
| Interferon gamma | IFN-γ | 1 | 0.728 | .348 |
| Insulin growth factor I | IGF-I | 1 | 0.856 | .11 |
| Insulin growth factor II | IGF-II | 1 | 0.965 | .851 |
| Interleukin 1 alpha | IL1-α | 1 | 0.664 | .055 |
| Interleukin 2 | IL2 | 1 | 0.476 | *.034 |
| Interleukin 3 | IL3 | 1 | 0.746 | .364 |
| Interleukin 3 receptor b | IL3 Rb | 1 | 0.918 | .541 |
| Interleukin 6 | IL6 | 1 | 0.894 | .749 |
| Interleukin 7 | IL-7 | 1 | 0.862 | .435 |
| Interleukin 15 | IL-15 | 1 | 0.984 | .904 |
| Interleukin 17B receptor | IL-17B R | 1 | 0.934 | .602 |
| Keratinocyte-derived chemokine | KC | 1 | 0.693 | .323 |
| Monocyte chemotactic protein 1 | MCP-1 | 1 | 0.780 | .21 |
| Monokine induced by gamma interferon | MIG | 1 | 0.951 | .714 |
| Macrophage inflammatory protein 1 alpha | MIP-1-α | 1 | 0.930 | .607 |
| Macrophage inflammatory protein 1 gamma | MIP-1-γ | 1 | 0.955 | .422 |
| Macrophage inflammatory protein 2 | MIP-2 | 1 | 0.706 | .505 |
| Matrix metalloproteinase 2 | MMP-2 | 1 | 0.919 | .595 |
| Matrix metalloproteinase 3 | MMP-3 | 1 | 0.972 | .659 |
| Osteroprotegerin | Osteoprotegerin | 1 | 0.859 | .015 |
| Regulation upon activation normal T cell expressed and presumably secreted | RANTES | 1 | 0.757 | .23 |
| Stem cell factor | SCF | 1 | 0.824 | .435 |
| Stromal cell-derived factor 1 alpha | SDF-1 α | 1 | 0.804 | .459 |
| Thymus and activation-regulated chemokine | TARC | 1 | 0.680 | .228 |
| Thymus-expressed chemokine | TECK | 1 | 0.869 | .416 |
| Tissue inhibitor of metalloproteinase-1 | TIMP-1 | 1 | 0.791 | .154 |
| Tissue inhibitor of metalloproteinase-2 | TIMP-2 | 1 | 0.998 | .972 |
| Tumor necrotic factor alpha | TNF-α | 1 | 0.909 | .774 |
| Soluble tumor necrotic factor receptor 1 | sTNF RI | 1 | 0.698 | .238 |
| Soluble tumor necrotic factor receptor 2 | sTNF RII | 1 | 0.700 | .303 |
| Thrombopoetin | TPO | 1 | 0.881 | *.009 |
| Vascular cell adhesion molecule-1 | VCAM-1 | 1 | 0.953 | .84 |
| Vascular endothelial growth factor | VEGF | 1 | 0.957 | .646 |
| Vascular endothelial growth factor D | VEGF D | 1 | 0.732 | .078 |
| Upregulated | ||||
| Granulocyte colony-stimulating factor | G-CSF | 1 | 1.011 | .933 |
| Macrophage colony-stimulating factor | M-CSF | 1 | 1.049 | .078 |
| Interleukin-1 beta | IL1-beta | 1 | 1.461 | .679 |
| Interleukin 13 | IL13 | 1 | 1.195 | .679 |
| Leptin | Leptin | 1 | 30.348 | .419 |
| Macrophage inflammatory protein 3 beta | MIP-3β | 1 | 1.163 | .707 |
| Macrophage inflammatory protein 3 alpha | MIP-3α | 1 | 1.236 | .203 |
Five samples from each group were analyzed by the Ray Bio cytokine array analysis. The protein levels are expressed as fold change between the groups. *P<0.05.