Table 4.
Association of Reported Missed Doses with HIV RNA Viral Load of PHIV+ Youth and Caregivers by Adolescent Developmental Stage
| 9–12 years (n=157) | 13–15 years (n=145) | 16–19 years (n=53) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| VL ≤400 | VL >400 | VL ≤400 | VL >400 | VL ≤400 | VL >400 | |||||
| Response | n (%) | n (%) | pb | n (%) | n (%) | pb | n (%) | n (%) | pb | |
| 2-Day recalla – any missed doses in the past two days | ||||||||||
| Youth | Missed at least one dose | 7 (44) | 9 (56) | 0.371 | 3 (17) | 15 (83) | 0.033 | 0 (0) | 3 (100) | 0.283 |
| Not missed | 30 (56) | 24 (44) | 38 (45) | 46 (55) | 14 (40) | 21 (60) | ||||
| Caregiver | Missed at least one dose | 7 (50) | 7 (50) | 0.559 | 3 (25) | 9 (75) | 0.267 | 1 (25) | 3 (75) | 0.498 |
| Not missed | 45 (42) | 62 (58) | 40 (42) | 55 (58) | 10 (44) | 13 (56) | ||||
| Missed within past week | ||||||||||
| Youth | Missed at least one dose | 13 (33) | 26 (67) | 0.144 | 10 (32) | 21 (68) | 0.446 | 1 (10) | 9 (90) | 0.064 |
| Not missed | 41 (47) | 47 (53) | 38 (41) | 55 (59) | 14 (42) | 19 (58) | ||||
| Caregiver | Missed at least one dose | 13 (43) | 17 (57) | 0.985 | 4 (20) | 16 (80) | 0.054 | 2 (25) | 6 (75) | 0.555 |
| Not missed | 44 (43) | 58 (57) | 45 (44) | 58 (56) | 8 (36) | 14 (64) | ||||
| Missed within past month | ||||||||||
| Youth | Missed at least one dose | 17 (35) | 32 (65) | 0.131 | 15 (32) | 32 (68) | 0.250 | 2 (11) | 16 (89) | 0.007 |
| Not missed | 37 (47) | 41 (53) | 33 (43) | 44 (57) | 13 (52) | 12 (48) | ||||
| Caregiver | Missed at least one dose | 16 (32) | 34 (68) | 0.045 | 12 (29) | 30 (71) | 0.064 | 4 (24) | 13 (76) | 0.139 |
| Not missed | 41 (50) | 41 (50) | 37 (46) | 44 (54) | 6 (46) | 7 (54) | ||||
a
2-Day recall yes/no.
b
The p value corresponds to the comparison of proportion of youth with VL >400 copies/mL between youth who reported missing at least one dose and those who reported not missing any doses during the given time period.