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. Author manuscript; available in PMC: 2015 Jan 2.
Published in final edited form as: Ann Rheum Dis. 2012 Jun 23;72(3):418–426. doi: 10.1136/annrheumdis-2011-201203

Figure 1. TLR7 and TLR8 expression is increased in RA synovial tissue (ST) lining and sublining macrophages compared to normal (NL) ST.

Figure 1

NL, OA and RA ST were stained with anti-human TLR7 (A) or anti-human TLR8 (C) (original magnification × 200) and positive immunostaining was scored on a 0–5 scale (B and D). ST lining and sublining macrophage immunostaining are shown as mean ±SEM, (n=5–7). E. RA serial sections were stained with anti-TLR7, anti-TLR8 and anti-CD68 antibodies in order to distinguish TLR7 and TLR8 staining on RA ST lining and sublining macrophages (original magnification × 400). F. RA serial sections were stained with anti-TLR7 and anti-vimentin antibodies in order to co-localize TLR7 staining in RA ST fibroblasts (original magnification × 400).