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. 2014 May 30;36(3):85–93. doi: 10.14402/jkamprs.2014.36.3.85

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Copyright © 2014 by The Korean Association of Maxillofacial Plastic and Reconstructive Surgeons. All rights reserved.

This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 1. — Expression and distribution of lymphangiogenic factors in oral squamous cell carcinoma; VEGF-C is expressed weakly in some tumor cells. VEGF-D is expressed in most tumor cells, tumor-associated endothelial cells, and immune cells in stroma. VEGFR-3 is expressed strongly in some tumor cells, endothelial cells, and macrophages. Phosphorylated VEGFR-3 is strongly expressed in invading tumor cells in poorly differentiated tumors. Upper panel belongs to lymph node- (L/N−) group and lower panel belongs to L/N+ group. The picture of pVEGFR-3 is the poorly group. Representative slides are shown (×200) (counterstained by Mayer’s hematoxyline).