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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: J Toxicol Environ Health A. 2015;78(1):15–31. doi: 10.1080/15287394.2015.958417

Figure 3. Inter-strain differences in liver toxicity of TCE in a sub-acute study.

Figure 3

Liver to body weight ratios (A), percent BrDU-positive hepatocyte nuclei (B), and liver expression of peroxisome proliferation marker genes Acox1 (C) and Cyp4a10 (D) were evaluated in mice treated with vehicle (white) or TCE (black; 600 mg/kg) for 5 days. Box and whiskers plots are shown (+, mean; line, median; box, inter-quartile range; whiskers, min to max). When box is shown, 4 animals per group were available. Otherwise, there were 3 animals per group. Asterisk (*) denotes a significant difference (p<0.05) compared to vehicle-treated group within same strain.