Skip to main content
. Author manuscript; available in PMC: 2015 Feb 21.
Published in final edited form as: Oncogene. 2013 Sep 16;33(34):4307–4315. doi: 10.1038/onc.2013.381

Figure 5. miR-93 down-regulates DAB2 expression by directly targeting the 3′UTR of the DAB2 mRNA.

Figure 5

A, The predicted interaction of miR-93 and the candidate target site in the DAB2 3′UTR with the predicted free energy of hybridization. The seed sequence is highlighted in red. B, H1993 cells were co-transfected with the indicated vectors. After 48 h of transfection, cells were lysed and luciferase activity was measured. Shown are normalized luciferase activities of different treatment groups. Differences in luciferase activity were assessed by two-tailed t-test. ***, p < 0.001.