Table 2.
Clinical, pathological and biological features of the SOX11low compared to SOX11high subgroups in the MCL2/3 cohort.
| Clinical and pathologic features | SOX11low n = 37 (32%) | SOX11high n = 77 (68%) | P-value* |
|---|---|---|---|
| Median age (years) | 54 (41–65) | 58 (37–65) | 0·108 |
| Age >60 years | 10/37 (27%) | 21/75 (28%) | 0·914 |
| Male sex | 27/37 (73%) | 56/75 (75%) | 0·848 |
| Blastoid morphology | 15/37 (41%) | 11/75 (15%) | 0·002 |
| CCND1weak | 4/37 (11%) | 3/75 (4%) | |
| CCND1intermediate | 18/37 (49%) | 21/75 (28%) | 0·006 |
| CCND1strong | 15/37 (41%) | 51/75 (68%) | |
| TP53strong | 10/35 (29%) | 0/58 (0%) | ≤0·001 |
| MIPIlow | 18/37 (49%) | 42/74 (57%) | |
| MIPIintermediate | 9/37 (24%) | 19/74 (26%) | 0·276 |
| MIPIhigh | 10/37 (27 %) | 13/74 (17%) | |
| MKI67 (30–100%) | 20/35 (57%) | 18/62 (29%) | 0·006 |
*
Statistical significant P-values are shown in bold.