Table 1.

Predefined inclusion and exclusion criteria for the recruitment of subjects

Inclusion criteria

Age group between 18–75 years

Must have 10 or more natural teeth

Must have at least one root caries lesion

Teeth included in the study must not be crowned or compromised

Not having participated in another clinical trial in 6 months prior to this trial

Exclusion criteria

Medically unfit, or the presence of any hard or soft tissue tumors in the oral cavity

Patients undergoing radiation therapy

Ongoing fixed orthodontic appliance therapy

Open or active coronal decay

Undergone high-fluoride therapy 6 months prior to this trial

Local or systemic antibiotic therapy within the 6 months

Pregnancy, lactating, or hypersensitive to the trial test products

Acute progressive periodontitis