Table 4.
Changes observed in the combined mean surface hardness scores (all centers)
| Test group | Control group | Intergroup comparisona | |
|---|---|---|---|
| Observation time | |||
| T0 | 3.4 ± 0.61 | 3.4 ± 0.66 | P = 0.8757 |
| T1 | 2.9 ± 0.67 | 3.1 ± 0.75 | P = 0.1787 |
| T2 | 2.4 ± 0.81 | 2.8 ± 0.79 | P = 0.0067 |
| Intragroup comparisona | |||
| T0 versus T1 | P = 0.0008 | P = 0.0358 | |
| T0 versus T2 | P < 0.0001 | P < 0.0001 | |
| T1 versus T2 | P < 0.0001 | P = 0.0122 | |
Test Group, High-fluoride toothpaste (5000 ppm F); Control Group, Regular-fluoride toothpaste (1350 ppm F); T0, Baseline; T1, 3 months; T2, 6 months.
Significant treatment effect (P = 0.0090, anova) and effect of time-point (P < 0.0001); the interaction term treatment*time not significant (P = 0.1151).
Post hoc Bonferroni–Dunn correction for multiple comparisons, adjusted P-value for significance P = 0.0167.