Table 1.

Use of VMAT in patients with brain metastases

Source	Sample size	Dose regimes	Treatment planning
			PTV margins	MU	Arcs & energy	Treatment time
Awad et al.14	30 patients (1–8 lesions)	50 Gy/15fx 30 Gy/15fx WBRT	GTV + 2 mm	N/A	2 arcs 6 MV	3.43 min
Hsu et al.2	10 patients (1–3 lesions)	32.25 Gy/15fx	GTV + 2 mm	400/min	1 arc 6 MV	3–4 min
Huang10	17 patients (2–5 lesions)	N/A	GTV + 2 mm	600/min	3–5 partial arcs 6 MV	N/A
Lagerwaard et al.12	8 patients (1–5 lesions)	40 Gy/5fx 20 Gy/5fx WBR 20 Gy/5fx SIB	GTV + 2 mm	530/min	2 arcs 6 MV	3 min
Lee et al.1	9 patients (4–10 lesions)	30 Gy/12fx + 15 Gy/6fx (boost) OR 48 Gy/12fx with SIB	GTV + 1–2 mm	N/A	2 arcs (8 patients) 3 arcs (1 patient) 6 MV	3 min
Wang et al.13	12 patients (2–12 lesions)	18–20 Gy/ 1fx (SRS)	CTV + 2 mm	600/min	2 arcs 6 MV	7.1 mina
Weber et al.3	29 patients (1–4 lesions)	40 Gy/10fx	GTV + 3 mm	600/min	2 arcs 6 MV	N/A

Gy, Gray; fx, fractions; MV, megavoltage; GTV, gross tumour volume; PTV, planning treatment volume; MU, monitor units; WBR, whole brain radiotherapy; SIB, simultaneous integrated boost; N/A, not available.

^aLonger time due to stereotactic dose being delivered.