Table 2.

Association between PPARγ2 CG/GG genotype (Ala variant) and serum lipids in HIV/HCV coinfected patients

	CC	CG/GG	p-value (a)	aAMR (95% CI)	p-value (b)
TC (mg/dL)	156.0 (63.0)	139.0 (49.0)	0.008	0.87 (0.79; 0.95)	0.004
TG (mg/dL)	122.0 (49.0)	122.0 (27.0)	0.319	0.92 (0.81; 1.04)	0.163
LDL-C (mg/dL)	86.4 (54.1)	72.4 (36.0)	0.005	0.79 (0.68; 0.93)	0.004
HDL-C (mg/dL)	36.0 (18.0)	36.0 (12.0)	0.921	0.98 (0.89; 1.09)	0.734
LDL-C/HDL-C	2.1 (1.3)	1.8 (1.1)	0.027	0.86 (0.73; 1.01)	0.067
AI	2.7 (1.6)	2.5 (1.4)	0.031	0.87 (0.76; 1.01)	0.069

Values expressed as median [interquartile range = upper quartile (Q3) - lower quartile (Q1)] and adjusted arithmetic mean ratio (aAMR) [95% of confidence interval (95% CI)]. Statistically significant differences are shown in bold. ^(a)P-values were calculated by generalized linear models (GLM) with gamma distribution (log-link). ^(b)P-values were calculated by GLM with log-link adjusted by the most important clinical and epidemiological characteristics (see Statistical analysis section).

Abbreviations: HCV hepatitis C virus, HIV human immunodeficiency virus, TC total cholesterol, TG triglycerides, LDL-C low density lipoprotein, HDL-C high density lipoprotein, LDL-C/HDL-C ratio of low density lipoprotein/high density lipoprotein, AI atherogenic index.