Figure ED5.

Abundance of Bacteroides XyGULs in human from a survey of metagenomic sequencing data from a total of 250 adult human samples (211 healthy, 27 ulcerative colitis, 12 Crohn’s Disease; see Methods for references). Datasets were individually queried by BLAST using the entire XyGUL nucleotide sequence from each of the four Bacteroides species listed at the top (cf. Fig. 2) and a PUL involved in degrading the red algal polysaccharide porphyran. Each horizontal line represents the presence or absence of a hit in a single individual. The leftmost column summarizes the total XyGUL content in each person (annotated according to the color key in the upper right corner). The XyGUL frequency across all 250 samples is shown at the bottom for each condition. The graph at the far right illustrates the variation in sequencing depth for each sample/study: black lines show the average depth in megabasepairs (Mbp) for each study; the light gray line shows the depth for each individual sample.