Table 3.
Improvement of symptoms according to on-demand ACS strategy and usual treatment strategy
| At the last follow-up visit | On-demand Strategy | Usual treatment strategy | p-value | NNT | |||
|---|---|---|---|---|---|---|---|
| % | n/N | % | n/N | Mean | 95% CI | ||
| Responder rate | 58.6 | 126/215 | 35.9 | 74/206 | 0.0001 | 5 | 4–8 |
| No abdominal pain | 36.9 | 82/222 | 15.5 | 32/206 | 0.0001 | 5 | 4–8 |
| No bloating | 32.9 | 73/222 | 10.6 | 22/207 | < 0.0001 | 5 | 4–7 |
| Patients in remission (IBS-SSS score < 75) | 37.7 | 81/215 | 16 | 33/206 | < 0.0001 | 5 | 4–8 |
n = number of patients fulfilling the criteria; N = total number of patients with available data.
Responder: decrease ≥ 50% of the IBS-SSS score.