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Minimum observable effect size estimated from segmentations of DESPOT1 acquisitions in sub‐cortical and cortical brain regions with images registered to standard MNI space by linear and non‐linear mappings as a function of (a) the proportion of the total sample of 180 participants attending centre 3 and (b) holding the number of participants attending centres 1 and 2 constant and varying the number of participants attending centre 3.
