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. 2013 Nov 8;54(1):97–108. doi: 10.1002/jcph.198

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© 2014 The Authors. The Journal of Clinical Pharmacology Published by Wiley Periodicals, Inc. on behalf of The American College of Clinical Pharmacology

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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(A) Individual netupitant NK₁ receptor occupancy (NK₁-RO) in the striatum at different time and doses; (B) Individual netupitant NK₁-RO in all tested brain regions at 6, 24, 48, 72, and 96 hours. Data are mean (SD), CV%.