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. 2014 Jan 29;20(4):527–534. doi: 10.1111/hae.12371

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© 2014 The Authors. Haemophilia published by John Wiley & Sons Ltd.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Fig 2 — Mean change in HAEMO-QOL total score for each version from baseline to end-of-treatment, according to the type of regimen patients received within the 12 months preceding the trial. A negative change in HAEMO-QOL total score indicates improved HRQoL. (OD: on-demand/M: mixed regimen/P: prophylaxis). Box plots present the following: interquartile range (Q1–Q3); +: mean; −: median; bottom and top bars: observed minimum and maximum observed values; ○: outliers (i.e. values that are outside the distance of 1.5 times the interquartile range from Q1 or Q3).