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Percentages of patients with specified increases in weekly CSBM frequency and SBM frequency at week 12 (pooled IBS-C phase 3 ITT population). At week 12, a greater percentage of patients treated with linaclotide met incremental levels of increase in weekly CSBM frequency and SBM frequency compared with placebo patients (p < 0.0001 for linaclotide compared with placebo for each level of improvement using Fisher's exact test for both CSBM and SBM frequency).
