Table 1.
Patient demographic summary by treatment group.
| Variable | CNI withdrawal N = 49 | Control N = 47 | Steroid withdrawal N = 30 | Total N = 126 |
|---|---|---|---|---|
| Recipient age in years (SD) | ||||
| Mean | 48.4 (10.17) | 45.8 (10.83) | 43.5 (10.66) | 46.3 (10.63) |
| Range | 24–65 | 20–64 | 23–62 | 20–65 |
| Gender, n (%) | ||||
| Male | 32 (65.3) | 34 (72.3) | 24 (80.0) | 90 (71.4) |
| Female | 17 (34.7) | 13 (27.7) | 6 (20.0) | 36 (28.6) |
| Race, n (%) | ||||
| Caucasian | 26 (53.1) | 25 (53.2) | 13 (43.3) | 64 (50.8) |
| Black | 0 (0.0) | 0 (0.0) | 1 (3.3) | 1 (0.8) |
| Asian | 19 (38.8) | 19 (40.4) | 14 (46.7) | 52 (41.3) |
| Pacific Islander | 0 (0.0) | 3 (6.4) | 1 (3.3) | 4 (3.2) |
| Other | 4 (8.2) | 0 (0.0) | 1 (3.3) | 5 (4.0) |
| Body Mass Index in kg/m2 (SD) | ||||
| Mean | 25.1 (4.45) | 25.0 (3.88) | 26.2 (3.86) | 25.3 (4.11) |
| Range | 16.5–34.4 | 17.4–32.0 | 20.5–35.1 | 16.5–35.1 |
| End-stage disease leading to transplantation, n (%) | ||||
| Glomerular disease | 24 (49.0) | 17 (36.2) | 10 (33.3) | 51 (40.5) |
| Pyelonephritis | 0 (0.0) | 1 (2.1) | 0 (0.0) | 1 (0.8) |
| Polycystic disease | 5 (10.2) | 9 (19.1) | 1 (3.3) | 15 (11.9) |
| Hypertension/nephrosclerosis | 1 (2.0) | 4 (8.5) | 6 (20.0) | 11 (8.7) |
| Drug-induced toxicity | 1 (2.0) | 0 (0.0) | 0 (0.0) | 1 (0.8) |
| Diabetes mellitus | 3 (6.1) | 2 (4.3) | 1 (3.3) | 6 (4.8) |
| Interstitial nephritis | 0 (0.0) | 2 (4.3) | 0 (0.0) | 2 (1.6) |
| Vasculitis | 0 (0.0) | 0 (0.0) | 1 (3.3) | 1 (0.8) |
| Obstructive disorder/reflux | 2 (4.1) | 2 (4.3) | 1 (3.3) | 5 (4.0) |
| Unknown origin | 10 (20.4) | 9 (19.1) | 7 (23.3) | 26 (20.6) |
| Other | 3 (6.1) | 1 (2.1) | 3 (10.0) | 7 (5.6) |
| Number of HLA mismatches, n (%) | ||||
| None | 3 (6.1) | 6 (12.8) | 2 (6.7) | 11 (8.7) |
| One | 8 (16.3) | 5 (10.6) | 0 (0.0) | 13 (10.3) |
| Two | 9 (18.4) | 6 (12.8) | 3 (10.0) | 18 (14.3) |
| >two | 27 (55.1) | 27 (57.4) | 24 (80.0) | 78 (61.9) |
| Missing | 2 (4.1) | 3 (6.4) | 1 (3.3) | 6 (4.8) |
| Number of previous renal transplantations, n (%) | ||||
| None | 47 (95.9) | 46 (97.9) | 30 (100.0) | 123 (97.6) |
| One transplantation | 1 (2.0) | 1 (2.1) | 0 (0.0) | 2 (1.6) |
| Missing | 1 (2.0) | 0 (0.0) | 0 (0.0) | 1 (0.8) |
| Cold ischaemia time in hours (SD) | ||||
| Mean | 6.2 (4.90) | 5.2 (4.60) | 7.3 (6.87) | 6.1 (5.35) |
| Range | 0.1–16.0 | 0.3–20.0 | 0.1–24.5 | 0.1–24.5 |
| Donor age in years (SD) | ||||
| Mean | 48.6 (12.60) | 40.8 (13.13) | 48.1 (13.66) | 45.5 (13.47) |
| Range | 16–70 | 9–71 | 23–71 | 9–71 |
| Donor characteristics, n (%) | ||||
| Cadaveric heart beating | 20 (40.8) | 15 (31.9) | 13 (43.3) | 48 (38.1) |
| Cadaveric nonheart beating | 2 (4.1) | 1 (2.1) | 1 (3.3) | 4 (3.2) |
| Living related | 17 (34.7) | 22 (46.8) | 12 (40.0) | 51 (40.5) |
| Living unrelated | 10 (20.4) | 9 (19.1) | 4 (13.3) | 23 (18.3) |