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Confocal laser microscopic observation of parvalbumin (PV) and calcium-binding protein-D-28 K (CaBP28K) fluorescence in Purkinje cells of a control subject (A–C), and case 1 with spinocerebellar ataxia type 31 (SCA31) (D–F). The atrophic Purkinje cells of the SCA31 cases have many dendritic processes (somatic sprouting), which consist of a surrounding halo-like amorphous materials (D–F). Bars; 20 μm.
