Table 4.

Correlations between white matter (WM) pathology and markers of axonal damage

Spearman's rho		SMI32	n	APP	n	WM score	n	GFAP count/0.5 mm2	n
SMI32
APP	NS	23
WM score	0.517***	40	0.364**	71
GFAP count/0.5 mm2	NS	22	−0.256*	68	NS	69
Sclerotic index	0.346*	40	0.283*	72	0.543***	125	NS	69

Values show Spearman's rho correlations for number (n) values analysed. Statistical significance was designated by following P values

^***P < 0.001

^**P < 0.01

^*P < 0.05.

Abbreviations: SMI32, nonphosphorylated neurofilament H length density; APP, amyloid precursor protein; GFAP count/0.5 mm², glial fibrillary acid protein cell count per 0.5 mm²; NS, not significant.