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Summary of VAS and POMS-B treatment effects. Significant effects are seen in GSK1521498 treatment periods at the 4-hour time point and in the GSK1521498 and ethanol periods at 7 hours on the VAS alertness and contentedness and POMS-B total mood disturbance. No effects are seen on VAS calmness. Ethanol was administered after the 4-hour time point, so there is no PD effect of ethanol at this time point (*P < .05).
