TABLE V.

Comparison of Clinical Features Among Children With HRSV Re-Infection and Who Were Infected 3 Times

Patterns of occurrence	Re-infection					Repeated infection 3 times
	No. of children	Fever		Dyspnoea		No. of children	Fever		Dyspnoea
		Mean no. of febrile days ± SD	P-Value	Rate of dyspnoea	P-Value		Mean no. of febrile days ± SD	P-Value	Rate of dyspnoea	P-Value
A–A*	47	F = 2.1 ± 0.3	0.95	F = 28/47**	0.004	33 (8, 11, 14)	Fs = 1.1 ± 0.3	0.23	Fs = 16/33	0.45
		S = 2.1 ± 0.3		S = 14/47			St = 1.6 ± 0.3		St = 20/33
B–B	9	F = 2.4 ± 0.6	0.89	F = 5/9	0.61	6 (3, 2, 1)	Fs = 1.8 ± 0.9	0.58	Fs = 2/6	>0.99
		S = 2.6 ± 0.6		S = 7/9			St = 1.0 ± 0.7		St = 2/6
A–B	33	F = 2.4 ± 0.3	0.31	F = 16/33	>0.99	16 (7, 4, 5)	Fs = 0.7 ± 0.3***	0.04	Fs = 7/10	0.46
		S = 1.9 ± 0.3		S = 16/33			St = 2.1 ± 0.5		St = 4/10
B–A	40	F = 2.1 ± 0.3	0.26	F = 24/40	0.5	32 (11, 12, 9)	Fs = 2.6 ± 0.3	0.33	Fs = 15/32	>0.99
		S = 2.5 ± 0.3		S = 21/40			St = 1.7 ± 0.3		St = 15/32
Total	129					87 (29 × 3)

^*The first letter designates the subgroup responsible for the first HRSV infection (in the re-infection) or the second infection (in the repeated infection 3 times); and the second letter, that for the second (re-infection) or third infection (repeated infection 3 times). The letter “F” indicates the first HRSV infection, “S” and “s” indicate the second, and “T” and “t” indicate the third infection. The numbers in parentheses indicate the number of patients between the first and second infection, the first and third, and the second and third, respectively. The Wilcoxon rank-sum test was used for comparing the mean duration of fever in each infection, and Fisher's exact test or Chi-square test was used for comparing the rate of dyspnoea at each infection. **, ***The differences are statistically significant.