Table 4.
Epilocus-specific methylation states significantly associated with parasite load or identified as FST outliers. Each epilocus is listed with size, type of methylation state (U = unmethylated, H = hemimethylated, M = fully methylated), sign of regression coefficient (β1 for GEE/sam and ρ for bayenv2) and strength of statistical support. Results for bayenv2 are given for separate analyses using either nonmethylated MSAP loci (NML) or a set of 260 neutral SNPs for neutral parameterization
Epilocus (MSAP band) | bayenv2b | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
ID | Name | Size | State ID | Type | Coefficient | GEEa | sama | NML | SNP | bayescanc | mchezad |
1 | MSAP_4.10_01 | 500 | ML201 | U | – | ** | ** | 2 | *** | *** | |
ML234 | H | + | ** | *** | *** | ||||||
2 | MSAP_3.12_05 | 400 | ML189 | H | + | 2** | *** | *** | |||
ML245 | U | – | *** | *** | |||||||
3 | MSAP_3.12_04 | 450 | ML192 | M | + | 2 | *** | *** | |||
ML244 | U | – | 2 | *** | *** | ||||||
4 | MSAP_2.17_02 | 475 | ML238 | M | – | *** | *** | ||||
ML117 | U | + | ** | 3 | 4 | ||||||
5 | MSAP_2.13_10 | 275 | ML159 | M | + | 3 | 2 | *** | |||
6 | MSAP_2.13_03 | 500 | ML224 | H | – | 3 | 2** | *** | |||
ML220 | U | + | 3 | 3*** | |||||||
7 | MSAP_2.6_09 | 300 | ML202 | H | + | *** | ** | 3 | 2** | *** | ** |
ML218 | U | – | ** | ** | 3 | 2 | ** | ||||
8 | MSAP_3.16_01 | 600 | ML209 | H | + | ** | ** | 3 | 2 | ** | |
ML128 | U | – | ** | * | |||||||
9 | MSAP_4.13_04 | 450 | ML207 | H | + | ** | 3 | * | |||
10 | MSAP_4.10_15 | 125 | ML98 | U | – | ** | * | ||||
ML194 | M | + | ** | ** | 2 | ||||||
11 | MSAP_3.16_17 | 130 | ML172 | U | – | ** | ** | ||||
12 | MSAP_3.12_01 | 600 | ML204 | H | + | ** | ** | 4 | 3** | ||
ML210 | U | – | 3 | 2 | |||||||
13 | MSAP_4.13_08 | 250 | ML213 | H | + | ** | ** | 2 | 2 | ||
14 | MSAP_2.17_14 | 160 | ML228 | U | – | ** | ** | ||||
15 | MSAP_3.16_07 | 320 | ML272 | M | – | ** | ** | 2 | 2 | ||
16 | MSAP_4.10_05 | 390 | ML143 | U | + | ** | 2 | 3 | |||
17 | MSAP_3.6_09 | 225 | ML100 | M | – | * | * | ||||
18 | MSAP_4.13_06 | 390 | ML284 | H | + | * | * | 4 | 3 | ||
19 | MSAP_3.12_09 | 320 | ML288 | M | + | * | * | ||||
20 | MSAP_4.13_01 | 600 | ML99 | U | – | * | * | ||||
21 | MSAP_4.13_11 | 150 | ML275 | H | + | * | |||||
22 | MSAP_3.12_02 | 550 | ML105 | M | + | 4 | 4** | ||||
23 | MSAP_2.6_01 | 600 | ML107 | H | + | 4 | 4* | ||||
24 | MSAP_3.16_03 | 500 | ML153 | U | – | 2 | |||||
ML262 | H | + | 2 | 2** | |||||||
25 | MSAP_3.16_13 | 200 | ML281 | M | – | 3 | 3 |
*: absolute value of coefficient outside 5% / 95% percentiles; **: P ≦ 0.05; ***: q ≦ 0.1.
2: |ρ| ≧ 0.2; 3: |ρ| ≧ 0.3; 4: |ρ| ≧ 0.4; **: Bayes factor ≧ 2; ***: Bayes factor ≧ 3.
***: q ≦ 0.05.
*: P ≧ 0.90; **: P ≧ 0.95; ***: P ≧ 0.99.