Table 2.
Clinical and histological data.
| Median | Range | |
|---|---|---|
| Time from the onset of diarrhoea to biopsy (days) | 22 | 8–33 |
| Time from the first dialysis to biopsy (days) | 12 | 6–22 |
| Patient characteristics | ||
| n | 10 | |
| Age (years) | 30 | 22–44 |
| Females (%) | 8 (80) | |
| Biochemical parameters at the time of kidney biopsy | ||
| Creatinine (mg/dl) | 2.08 | 1.2–7.44 |
| Platelet count (109/l) | 161 | 102–285 |
| LDH (U/l) | 239 | 165–412 |
| Haemodialysis (n, %) | 6 (60) | |
| Histological evaluation | ||
| Tubular epithelial flattening (n, %) | 10 (100) | |
| Tubular epithelial vacuolization (n, %) | 10 (100) | |
| Tubular intraluminal cell debris (n, %) | 5 (50) | |
| Chronic tubular damage and interstitial fibrosis (% area of cortex) | 3 | 0–10 |
| Glomeruli/biopsy | 12 | 6–41 |
| Percentage of segmentally sclerosed glomeruli (%) | 13 | 0–33 |
| Percentage of globally sclerosed glomeruli (%) | 7 | 0–63 |
| Glomerular intracapillary thrombi (n, %) | 4 (40) | |
| Glomerular intracapillary fragmentocytes (n, %) | 6 (60) | |
| Glomerular intracapillary mononuclear cells (n, %) | 5 (50) | |
| Glomerular intracapillary granulocytes (n, %) | 4 (40) | |
| Glomerular endothelial swelling (n, %) | 90 (90) | |
| Widening of the subendothelial space (n, %) | 6 (60) | |
| Loss of endothelial fenestrae (n, %) | 8 (80) | |
| Mesangial matrix expansion (n, %) | 6 (60) | |
| Mesangiolysis (n, %) | 8 (80) | |
| Podocyte swelling (n, %) | 3 (30) | |
| Arteriolar endothelial swelling (n, %) | 5 (50) |
Parameters are expressed as median or as proportions, as appropriate.