Table 3.
Variable | Group | Pretest | Overall | Day 8 | Day 32 | Day 92 | Day 155 | Day 184 | |
---|---|---|---|---|---|---|---|---|---|
APTT (sec) | Sham | Mean | 14.28 | 13.52 | 13.36 | 13.6 | 14.16 | 14.05 | 12.40 |
SD | 1.58 | 1.32 | 1.14 | 1.17 | 1.42 | 1.42 | 0.89 | ||
N | 8 | 40 | 8 | 8 | 8 | 8 | 8 | ||
P-value | – | ||||||||
8 mg/kg/day | Mean | 14.58 | 14.48 | 14.59 | 14.76 | 15.06 | 14.99 | 13.00 | |
SD | 1.84 | 1.9 | 2.32 | 2.02 | 1.77 | 1.7 | 1.12 | ||
N | 8 | 40 | 8 | 8 | 8 | 8 | 8 | ||
P-value | 0.1713 | ||||||||
16 mg/kg/day | Mean | 15.05 | 15.29 | 14.96 | 15.07 | 16.19 | 16.53 | 13.47 | |
SD | 1.46 | 2.05 | 1.76 | 1.23 | 1.63 | 2.62 | 1.58 | ||
N | 8 | 38 | 8 | 7 | 8 | 8 | 7 | ||
P-value | 0.0248* | ||||||||
24 mg/kg/day | Mean | 14.51 | 14.97 | 14.49 | 15.46 | 14.98 | 15.84 | 14.14 | |
SD | 2.17 | 1.78 | 1.73 | 1.82 | 0.96 | 2.66 | 1.10 | ||
N | 8 | 39 | 8 | 7 | 8 | 8 | 8 | ||
P-value | 0.0306* | ||||||||
40 mg/kg/day | Mean | 15.03 | 16.33 | 15.33 | 16.29 | 17.31 | 18.11 | 14.73 | |
SD | 1.58 | 2.85 | 1.68 | 2.95 | 2.40 | 4.04 | 1.99 | ||
N | 8 | 36 | 8 | 7 | 7 | 7 | 7 | ||
P-value | 0.0007** |
Statistically significant at the 0.05, and 0.01 level, respectively.