Table 1.

Key Developmental Genes Regulated by the LAFL Network

AGI Code	Gene Name	Protein Family	Cis-Element Enriched in LAFL Bound Promoter	Up-Regulated in val1 val2	LEC1	LEC2	FUS3	ABI3	References	Potential Function (TAIR)
AT5G47670	L1L	HAP3	Sph/RY; CCAAT box	√	√		√		10,15,18,24,28	Regulator of embryo development
AT1G28300	LEC2	B3	Sph/RY	√	√				10,12	Plays critical roles during early and late embryo development
At3g26790	FUS3	B3	Sph/RY	√	√	√	√	√	10,12–14,21,22,24	Regulator of gene expression during late embryogenesis
AT3G24650	ABI3	B3	Sph/RY; ABRE	√	√	√	√	√	10,12,14,22,24	Regulator of the transition between embryo maturation and early seedling development
AT2G30470	VAL1/HSI2	B3	Sph/RY				√		15,22	Repression of seed maturation program during germination
AT5G07500	PEI1	Zf	Sph/RY	√			√	√	10,15,21	Required for heart-stage embryo formation
AT3G15170	CUC1	NAC	Sph/RY	√			√		10,22	Shoot apical meristem formation and auxin-mediated lateral root formation
AT5G17430	BBM	AP2	—	√			√		10,22	Promotes cell proliferation, differentiation and morphogenesis, especially during embryogenesis
AT3G54320	WRI1	AP2	Sph/RY; ABRE	√	√	√	√		10,15,22–24	Control of lipid biosynthetic and metabolic processes
AT5G10140	FLC	MADS box	Sph/RY	√			√		10,15	A repressor of floral transition
AT5G13790	AGL15	MADS box	Sph/RY	√		√	√		10,15,22,26	Embryonic and post embryonic development
AT3G27785	MYB118	MYB	—					√	21	Regulates the embryonic pathway by up-regulating LEC1
AT1G03770	RING1b	PRC1	Sph/RY	√			√		10,22	Core component of Polycomb Repressive Complex1 (PRC1). Interacts physically with CLF and LHP1 and function together to repress target gene expression.
AT2G46685	MIR166	—	Sph/RY				√		22	Encodes a microRNA that targets several HD-ZIPIII family members including PHV and PHB