Table 3.
Association between serum concentrations of PFCs and risk for gestational diabetes (GDM), LIFE Study, 2005–2009.
| Unadjusted OR (95% CI) |
Adjusted OR1 (95% CI) |
Adjusted OR2 (95% CI) |
|
|---|---|---|---|
| PFOA (perfluorooctanoic acid) | |||
| Per SD increment (0.43) | 1.61 (1.05,2.49) | 1.85 (1.15,2.98) | 1.86 (1.14,3.02) |
| Et-PFOSA-AcOH (2-(N-ethyl-perfluorooctane sulfonamido) acetic acid)‡ | |||
| Per SD increment (0.05) | 1.26 (0.89,1.79) | 1.24 (0.87,1.79) | 1.25 (0.87,1.80) |
| Me-PFOSA-AcOH (2-(N-methyl-perfluorooctane sulfonamido) acetic acid) | |||
| Per SD increment (0.24) | 1.06 (0.72,1.55) | 1.06 (0.72,1.55) | 1.05 (0.71,1.54) |
| PFDeA (perfluorodecanoic acid) | |||
| Per SD increment (0.21) | 1.07 (0.73,1.55) | 1.07 (0.72,1.58) | 1.04 (0.70,1.53) |
| PFNA (perfluorononanoic acid) | |||
| Per SD increment (0.32) | 1.08 (0.73,1.60) | 1.09 (0.72,1.63) | 1.06 (0.70,1.60) |
| PFOSA (perfluorooctane sulfonamide)‡‡ | |||
| Per SD increment (0.03) | 1.08 (0.76,1.55) | 1.08 (0.76,1.55) | 1.07 (0.74,1.55) |
| PFOS (perfluorooctane sulfonic acid) | |||
| Per SD increment (0.55) | 1.15 (0.78,1.70) | 1.16 (0.77,1.76) | 1.13 (0.75,1.72) |
OR1 adjusted for age (years), BMI (kg/m2), and parity conditional on gravidity (never pregnant/pregnant without live birth/ pregnant with previous birth)
OR2 Adjusted for age (years), BMI (kg/m2), parity conditional on gravidity (never pregnant/pregnant without live birth/ pregnant with previous birth), race/ethnicity (White/non-White) and smoking (yes/no)
‡
95% concentrations for this analyte are below the LOD
‡‡
89% concentrations for this analyte are below the LOD
SD values presented were log transformed of the original SD