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. Author manuscript; available in PMC: 2016 Jan 1.

Published in final edited form as: Cancer Chemother Pharmacol. 2014 Nov 6;75(1):67–75. doi: 10.1007/s00280-014-2618-2

Fig. 3 — Visual predictive checks of lymphosuppression after HCT conditioning with Protocol 1519 (3A) or Protocol 2041 (3B). Black and red lines represent the median (solid) and 5^th and 95^th percentile (dashed) of the observed and simulated data, respectively. Start of simulations standardized to 72 hrs before fludarabine administration, showing the scheduled times of fludarabine (F), targeted busulfan (^TBU), rATG (rA), rest and graft administration.

Fig. 3 — Visual predictive checks of lymphosuppression after HCT conditioning with Protocol 1519 (3A) or Protocol 2041 (3B). Black and red lines represent the median (solid) and 5^th and 95^th percentile (dashed) of the observed and simulated data, respectively. Start of simulations standardized to 72 hrs before fludarabine administration, showing the scheduled times of fludarabine (F), targeted busulfan (^TBU), rATG (rA), rest and graft administration.