Table 4.
Significant clusters of neural activation in response to fearful facial expressions in healthy controls (n = 9).
Brain region (BA) | Talairach and Tournoux coordinates
|
||||
---|---|---|---|---|---|
x | y | z | Size | p | |
Fear (50%) vs. neutral | |||||
Left inferior parietal gyrus (BA40) | −43 | −33 | 48 | 20 | .00006 |
Right inferior temporal gyrus (BA20) | 36 | −43 | −18 | 16 | .001 |
Left cerebellum | −21 | −60 | −18 | 14 | .001 |
Medial frontal lobe (BA32) | 0 | 39 | 9 | 9 | .00007 |
Left inferior occipital gyrus (BA18) | −32 | −86 | −7 | 9 | .00006 |
Left hippocampus | −32 | −20 | −7 | 2 | .001 |
Fear (100%) vs. neutral | |||||
Left inferior temporal lobe (BA37) | −47 | −50 | −18 | 100 | .001 |
Right fusiform gyrus (BA37) | 32 | −46 | −18 | 46 | .002 |
Left fusiform gyrus (BA19) | −36 | −63 | −7 | 29 | .0005 |
Left cerebellum | −7 | −52 | −13 | 28 | .002 |
Right cerebellum | 32 | −50 | −24 | 36 | .00004 |
Left precuneus (BA7) | −25 | −43 | 53 | 13 | .0005 |
Left amygdala | −15 | −7 | −13 | 4 | .002 |
Right hippocampus | 32 | −43 | −2 | 3 | .002 |
Coordinates of regions in which significant within-group differences were demonstrated. Voxel-wise and cluster-wise differences at p = .05 and p = .003, respectively. Brodmann areas are indicated in parentheses. BA, Brodmann area.