Table 6.
Significant between-group differences in neural response to expressions of disgust and fear.
| No. | Brain region, BA | Emotion
|
Areas with significant differences
|
Direction of difference
|
||||
|---|---|---|---|---|---|---|---|---|
| Intensity | x | y | z | Size | Patients | Controls | ||
| 1. | L inferior temporal gyrus, BA37 | 100% D | −51 | 4 | −40 | 131 | Increase | Decrease |
| 2. | L middle temporal gyrus, BA21 | 100% D | −51 | −15 | −13 | 11 | Increase | Decrease |
| 3. | L insula | 100% D | −43 | − 11/−15 | −2/4 | 13 | Increase | Decrease |
| 4. | L orbito-frontal cortex, BA47 | 100% D | −18 | 22 | −24 | 4 | Increase | Decrease |
| 5. | R middle temporal gyrus, BA21 | 100% D | 54 | −4 | −29 | 91 | Increase | Decrease |
| 6. | R inferior temporal gyrus, BA37 | 100% D | 54 | −4/−15 | −24 | 18 | Increase | Decrease |
| 7. | L inferior parietal lobule, BA40 | 50% F | −40 | −26 | 26 | 62 | Decrease | Increase |
The regions in the table represent the components of main clusters produced by the 3 × 2 ANOVAs. Regions 1–4 constitute the large left frontal/temporal cluster with differential response to 100% disgust; regions 5 & 6 constitute right middle/inferior temporal cluster with differential response to 100% disgust; region 7 represents a cluster with differential response to 50% fear. BA, Brodmann area; D – disgust; F – fear.