Table 2.
Proportion of economic evaluations (n=53) that did not obtain full score, for each criterion. These criteria are listed and named according to the QHES instrument; ‘objectives’ represents Criterion 1, ‘perspectives’ represents Criterion 2, and so on.
| Question/Criterion | N (%) did not obtain full score | Reference(s) |
|---|---|---|
| Objectives | 14 (26) | (8, 34, 35, 43, 44, 47, 52, 54, 57, 64, 66, 73) |
| Perspectives | 34 (64) | (30-33, 35,36,37,38,39, 42, 44, 45, 47,48,49, 52, 53, 57-61, 63, 67,68,69,70,71,72, 74) |
| Variable estimate | 25 (47) | (31, 33-39, 41, 42, 44, 46, 49, 50, 52,53,54,55, 61, 63, 65, 67, 68, 72) |
| Subgroup analysis | 4 (67) out of 6 studies did not pre-specify subgroups. | (43, 46, 63, 73) |
| Uncertainty | 36 (69) | (30,31,32,33,34,35,36,37,38,39,40,41,42, 44, 45, 47,48,49,50, 52-54, 58, 61,62,63,64,65,66,67, 70,71,72,73,74) For ref. #51, only applies to CEA. |
| Incremental | 18 (35) did incremental analysis. Others NA due to CCA studies. | (7, 8, 35, 40, 43, 51, 55, 56, 58, 60, 62,63,64,65,66, 75) |
| Methodology | 1 (2) | (66) |
| Time horizon | 29 (56) did not do discounting. | (31, 32, 34-39, 41, 44, 49-51, 54, 59,60,61,62, 67, 68, 70, 71) |
| Costs | 22 (42) | (34, 35, 37, 39, 41, 42, 44, 47,48,49,50, 52,53,54, 57, 61, 67, 68, 70-72, 74) |
| Primary outcome | 36 (68) | (8, 32, 33, 35, 37,38,39, 41, 42, 44, 45, 47,48,49,50, 52, 54, 57, 59,60,61,62,63, 65,66,67,68, 71, 73, 74) |
| Valid reliable outcome | 0 | - |
| Model, methods, analysis | 16 (30) did not clearly display numerator and/or denominator components. | (37, 39, 40, 42,44, 47,50,52,57, 61,67, 68,70, 72, 74) |
| Assumptions and limitations | 20 (38) did not state and justify both main assumptions and limitations. | (33,34,35,38,43,57,58,59,60,61,67-69,71,72,73,74) |
| Bias | 39 (74) | (8, 31-38, 40, 43, 44, 48, 49, 51, 53, 55,56,57,58,59,60,61, 63, 64, 66,67,68,69,70,71,72, 74, 76) |
| Conclusion | 0 | - |
| Source of funding | 15 (29) | (30, 33, 34, 36, 37, 40, 42, 49, 53, 54, 67, 70, 72, 73) |