Table II.
Patient characteristics stratified by consistent annual hepatocellular carcinoma surveillance
| Patient Characteristics | Patient
with consistent hepatocellular carcinoma surveillance (n=98) |
Patients
without consistent hepatocellular carcinoma surveillance (n=632) |
p-value |
|---|---|---|---|
| Age | 54.6 ± 11.3 | 55.3 ± 10.6 | 0.56 |
| Gender (% Male) | 72 (73.5%) | 391 (61.9%) | 0.03 |
| Race/Ethnicity | 0.95 | ||
| Caucasian | 32 (32.7%) | 219 (34.7%) | |
| Black | 20 (20.4%) | 139 (22.0%) | |
| Hispanic | 44 (44.9%) | 256 (40.5%) | |
| Asian | 2 (2.0%) | 15 (2.4%) | |
| Etiology | 0.07 | ||
| Hepatitis C | 57 (58.2%) | 327 (51.7%) | |
| Hepatitis B | 4 (4.1%) | 21 (3.3%) | |
| Alcohol | 30 (30.6%) | 166 (26.3%) | |
| Nonalcoholic steatohepatitis | 6 (6.1%) | 99 (15.7%) | |
| Insurance status | 0.49 | ||
| Medicare | 33 (33.7%) | 230 (36.5%) | |
| Medicaid | 18 (18.4%) | 126 (20.0%) | |
| Private Insurance | 7 (7.1%) | 24 (3.8%) | |
| Uninsured | 40 (40.8%) | 250 (39.7%) | |
| Preferred language (% English) | 72 (73.5%) | 473 (75.1%) | 0.71 |
| Functional status (% ECOG 0–2) | 79 (98.8%) | 495 (98.4%) | 1.0 |
| Alcohol (% active) | 18 (19.0%) | 139 (23.2%) | 0.69 |
| HIV status (% positive) | 9 (16.1%) | 50 (12.4%) | 0.40 |
| Presence of ascites | 38 (38.8%) | 233 (36.9%) | 0.72 |
| Presence of hepatic encephalopathy | 25 (25.5%) | 126 (19.9%) | 0.21 |
| Platelet count * 1000/mm3 | 88 (4–234) | 98 (3 – 476) | 0.008 |
| AST (U/L) | 54 (16 – 280) | 55 (9 – 1008) | 0.41 |
| ALT (U/L) | 37 (11 – 333) | 38 (5 – 2253) | 0.68 |
| Bilirubin (mg/dL) | 1.3 (0.2 – 32.8) | 1.0 (0.1 – 30.0) | 0.14 |
| Albumin (g/dL) | 3.4 (1.2 – 4.8) | 3.5 (1.2 – 4.8) | 0.84 |
| Creatinine (mg/dL) | 0.9 (0.4 – 10.3) | 0.9 (0.1 – 12.8) | 0.11 |
| INR | 1.2 (0.9 – 4.0) | 1.2 (0.9 – 6.3) | 0.94 |
| Child Pugh score | 7 (5–13) | 7 (5 – 14) | 0.54 |
| Child Pugh classification | 0.63 | ||
| Child Pugh A | 39 (40.2%) | 266 (44.5%) | |
| Child Pugh B | 42 (43.3%) | 228 (38.1%) | |
| Child Pugh C | 16 (16.5%) | 104 (17.4%) | |
| Number of primary care clinic visits per year | 2.3 (0 – 12.7) | 2.3 (0 – 13.2) | 0.50 |
| Number of hepatology clinic visits per year | 1.0 (0 – 11.0) | 0.7 ( 0 – 10.5) | 0.002 |
All data are expressed as median (range) unless otherwise specified
ALT – alanine aminotransferase; AST – aspartate aminotransferase; ECOG – Eastern Cooperative Oncology Group; INR – international normalized ratio