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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Mol Immunol. 2014 Nov 15;64(1):9–17. doi: 10.1016/j.molimm.2014.10.017

Figure 2. Factor D deficient mice have exacerbated CCl4-induced liver ALT activity.

Figure 2

WT, C1qa−/−, C4−/− and FD−/− mice were exposed to a single injection of CCl4 and plasma ALT was measured at A. 48 hr and B. WT and FD−/− mice ALT levels at 24, 48 and 72 hr. N=5–8 mice per group. C. Immunoblots of total hepatic protein from control WT and FD−/− mice were performed to determine baseline expression of cytochrome P450 2E1 (CYP2E1). Quantification of band intensity measured by densitometry after normalization to HSC70 is shown in the bar graphs. n = 4 mice per group. Values represent mean ± standard error of mean. Values with different alphabetical superscripts or points represented by an (*) were significantly different from each other, p<.05.