Table 2.
Univariate Analysis of Predictors on Delayed Post-Endoscopic Submucosal Dissection Bleeding
| Occurred (11 lesions) | Not occurred (536 lesions) | p-value | ||||
|---|---|---|---|---|---|---|
|
| ||||||
| Total | 2nd-look (2 lesions) | No 2nd-look (9 lesions) | p-value | |||
| Age | 58.3±9.5 | 52.0±18.4 | 59.7±7.7 | 0.660 | 62.5±9.7 | 0.156 |
| Male sex | 9 (81.8) | 2 (100.0) | 7 (77.8) | 1.000 | 399 (74.4) | 0.738 |
| Comorbidities | ||||||
| Hypertension (present) | 4 (36.4) | 1 (50.0) | 3 (33.3) | 1.000 | 199 (37.1) | 1.000 |
| Diabetes mellitus (present) | 1 (9.1) | 0 | 1 (11.1) | 1.000 | 95 (17.7) | 0.699 |
| Heart disease (present) | 1 (9.1) | 0 | 1 (11.1) | 1.000 | 10 (1.9) | 0.202 |
| Anticoagulants/platelets (used) | 2 (18.2) | 1 (50.0) | 1 (11.1) | 0.345 | 51 (9.5) | 0.289 |
| Histologic type | ||||||
| Adenoma/adenocarcinoma | 4/7 | 0/2 | 4/5 | 0.491 | 208/328 | 1.000 |
| Location | ||||||
| Upper/mid/lower third | 0/2/9 | 0/1/1 | 0/1/8 | 0.345 | 38/165/333 | 0.366 |
| AW/PW/LC/GC | 1/2/6/2 | 0/0/2/0 | 1/2/4/2 | 0.565 | 94/87/225/130 | 0.793 |
| Macroscopic type | ||||||
| Elevated/flat or depressed | 7/4 | 1/1 | 6/3 | 1.000 | 404/132 | 0.479 |
| Size of the tumor, mm | 22.8±9.9 | 28.0±14.1 | 21.7±9.4 | 0.441 | 15.1±10.5 | 0.016 |
| ≥15 | 10 (90.9) | 2 (100.0) | 8 (88.9) | 1.000 | 223 (41.6) | 0.001 |
| ≥20 | 7 (63.6) | 1 (50.0) | 3 (66.7) | 1.000 | 136 (25.4) | 0.009 |
| Size of the resected specimen, mm | 48.0±13.7 | 50.0±14.1 | 47.6±13.4 | 0.832 | 43.1±13.3 | 0.226 |
| Resection style, en bloc/piecemeal | 11/0 | 2/0 | 9/0 | 1.000 | 512/24 | 1.000 |
| Procedure time, min | 64.3±19.8 | 77.5±13.4 | 61.3±20.3 | 0.321 | 66.1±39.4 | 0.879 |
| Antiulcer medication after ESD, PPIs/H2RAs | 2/9 | 1/1 | 1/8 | 0.345 | 127/409 | 1.000 |
Data are presented as mean±SD or number (%).
AW, anterior wall; PW, posterior wall; LC, lesser curvature; GC, great curvature; ESD, endoscopic submucosal dissection; PPIs, proton pump inhibitors; H2RAs, histamine-2 receptor antagonists.