Enrichments of D7 cortisone (A and B) and D7 cortisol (C and D) observed in microdialysis effluent of abdominal (left panel) and leg (right panel) sc adipose tissue. Microdialysate samples were collected over 4 hours of D7 cortisone infusion in LND (white bar), OND (shaded bar), and ODM (black bar). *, P = .001 vs 0; †, P < .001 vs LND and OND. MPE, mole percent excess.