Table 1.
Baseline | Visit 5a | Visit 10a | |
---|---|---|---|
n | 3266 | 1628 | 1703 |
Age, median (IQR), y | 46 (4) | 51 (4) | 56 (4) |
BMI, median (IQR), kg/m2 | 26.64 (9.28) | 27.35 (9.78) | 27.68 (9.76) |
Race/ethnicity | |||
African American | 920 (28.2) | 443 (27.2) | 511 (30) |
Caucasian | 1535 (47) | 733 (45) | 824 (48.4) |
Chinese | 249 (7.6) | 164 (10.1) | 175 (10.3) |
Hispanic | 285 (8.7) | 97 (6) | N/A |
Japanese | 277 (8.5) | 191 (11.7) | 193 (11.3) |
Health status | |||
Worse | 513 (15.8) | 241 (15) | 247 (14.5) |
Same | 2028 (62.6) | 522 (32.5) | 584 (34.4) |
Better | 699 (21.6) | 845 (52.5) | 867 (51.1) |
Menopausal status | |||
Pre | 1713 (53.7) | 94 (5.8) | 5 (0.3) |
Early peri | 1477 (46.3) | 763 (46.9) | 129 (7.6) |
Late peri | N/A | 227 (14) | 115 (6.8) |
Post | N/A | 495 (30.4) | 1310 (76.9) |
Surgical | N/A | 48 (3) | 144 (8.5) |
Hot flashes | |||
None | 2382 (73.3) | 847 (52.2) | 837 (49.3) |
1–5 d | 617 (19) | 447 (27.5) | 453 (26.7) |
6+ d | 252 (7.8) | 330 (20.3) | 407 (24) |
Night sweats | |||
None | 2299 (70.7) | 989 (60.9) | 1097 (64.6) |
1–5 d | 735 (22.6) | 438 (27) | 378 (22.2) |
6+ d | 216 (6.6) | 197 (12.1) | 224 (13.2) |
Vaginal dryness | |||
None | 2616 (80.7) | 1122 (69.3) | 1108 (65.3) |
1–5 d | 453 (14) | 320 (19.8) | 289 (17) |
6+ d | 174 (5.4) | 178 (11) | 301 (17.7) |
Use of lubricants | |||
Never | 1888 (73.9) | 708 (63.6) | 417 (43.8) |
Sometimes/almost never | 435 (17) | 212 (19) | 231 (24.3) |
Always/almost always | 184 (7.2) | 158 (14.2) | 259 (27.2) |
No intercourse | 47 (1.8) | 36 (3.2) | 44 (4.6) |
Overall health | |||
Fair/poor | 513 (15.8) | 241 (15) | 247 (14.5) |
Good | 2028 (62.6) | 522 (32.5) | 584 (34.4) |
Very good | 438 (13.5) | 612 (38.1) | 634 (37.3) |
Excellent | 261 (8.1) | 233 (14.5) | 233 (13.7) |
Depression | |||
Not depressed | 2467 (75.6) | 1311 (80.7) | 1430 (84.4) |
Depressed | 795 (24.4) | 314 (19.3) | 265 (15.6) |
Current smoker | |||
No | 2675 (82.7) | 1423 (87.5) | 1502 (88.4) |
Yes | 560 (17.3) | 203 (12.5) | 197 (11.6) |
Abbreviations: IQR, interquartile range; N/A, not applicable. Data are expressed as number (percentage) unless otherwise stated.
Women reporting hormone therapy at a follow-up visit were excluded. At baseline, no women were on hormone therapy per protocol. At visit 5, 221 (11.95%) of 1849 women were hormone users; at visit 10, 128 (6.99%) of 1831 women were hormone users.