Table 1.
Demographic and Clinical Characteristics of Study Group (n = 263)
| Characteristics | Value |
|---|---|
| Age, y | 9.7 ± 4.1 |
| Age group, y, n | |
| 0–4 | 14% (37) |
| 5–9 | 37% (96) |
| 10–14 | 40% (106) |
| 15–18 | 9% (24) |
| Gender (% male), n | 59% (155) |
| Race, white/black/other, % | 94/5/1 |
| BMI percentile at onset | 51.3 ± 34.5 |
| BMI Z score at onset | −0.0 ± 1.5 |
| BMI percentile at 3 mo | 73.2 ± 22.4a |
| BMI Z score at 3 mo | 0.8 ± 0.9a |
| Waist class at 3 mo, % >75th percentile, n | 67% (129) |
| Height Z score at 3 mo | 0.4 ± 1.0b |
| WHtR at 3 mo | 0.5 ± 0.1c |
| Centrally obese, %, n | 30% (57) |
| C-peptide at onset, ng/mL | 0.6 [0.2, 0.9]d |
| C-peptide at 3 mo, ng/mL | 1.4 [0.7, 2.5]e |
| HbA1c at onset, % | 11.7 ± 2.5 |
| HbA1c at 3 mo, % | 7.4 ± 0.8 |
| HLA DQ2 and DQ8, %, n | |
| XX | 17% (41) |
| DQ2 | 30% (72) |
| DQ8 | 36% (89) |
| DQ2/DQ8 | 17% (42) |
| ICA h, % positive, n | 84% (222) |
| GAD-65, % positive, n | 56% (148) |
| IA2, % positive, n | 73% (193) |
| IAA, % positive, n | 64% (68) |
Data are mean ± SD unless otherwise noted. C-peptide is presented as median [interquartile range].
Based on 247 subjects.
Based on 253 subjects.
Based on 192 subjects.
Based on 244 subjects.
Based on 219 subjects.