Figure 1.
Primary outcome: Least squares (LS) mean of treatment differences from placebo for QTcF change from baseline (ΔΔQTcF) and 90% confidence intervals show lack of effect for tafenoquine: upper 90% CI <10 milliseconds at all time points. Assay sensitivity was confirmed with the positive moxifloxacin control: lower 95% CI ≥5 milliseconds for at least one time point (5.0 milliseconds at 4 hours).