Table 1.
The inclusion and the exclusion criteria for the Pilot-CRAfT study
| Inclusion criteria: | |
| 1) | Permanent or long-standing persistent AF (definitions according to the latest ESC guidelines on AF) |
| 2) | At least three months after the procedure of a CRT device implantation |
| 3) | A CRT device with the presence of a right atrial electrode |
| 4) | Age: ≥18 years old |
| 5) | Effectively biventricular paced captured beats percentage <95% |
| 6) | Effective therapy with oral anticoagulants for at least three weeks |
| 7) | Written informed consent |
| Exclusion criteria: | |
| 1) | Reversible causes of AF |
| 2) | Significant valve disease |
| 3) | Advanced AV block (including: AVJA) |
| 4) | Contraindications to amiodarone (hyperthyroidism, non-compensated hypothyroidism, drug intolerance, QT >460 ms for men, QT >450 ms for women) |
| 5) | Long-QT syndrome |
| 6) | Cardiac transplantation in six months |
| 7) | Life expectancy less than one year |
| 8) | LA diameter larger than 6 cm |
| 9) | Heart failure decompensation within 48 hours before the qualification |
| 10) | Chronic dialysis |
| 11) | History of alcohol abuse |
| 12) | Pregnancy or lack of effective contraceptive therapy (in case of females in the reproductive age) |
| 13) | Participation in other clinical trial |
AF, atrial fibrillation; AV, atrioventricular; AVJA, atrioventricular junction ablation; CRT, cardiac resynchronization therapy; ESC, European Society of Cardiology; LA, left atrium.