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. 2014 Aug 12;12:213. doi: 10.1186/s12967-014-0213-2

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© Schäfer et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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FET values for patients suffering from MCAD. Data represent the individual FET values of MCAD patients, derived group means (black horizontal lines), and the optimal cut-off value (red horizontal line) of 0.945 with 0.0% misclassification. Data were statistically analyzed using the Student’s t-test for unpaired values and ROC analysis, respectively. Control: healthy individuals (n = 20), MCAD: patients with mast cell activation disease (n = 22); (A) MCAS: MCAD patients with mast cell activation syndrome (n = 12); SM: MCAD patients with systemic mastocytosis (n = 10); (B) MCAD-M: MCAD patients without MCAD-specific medication (n = 9); MCAD + M: MCAD patients with MCAD-specific medication (n = 13).