Table 4.
Subjects' volume of distribution (VT) obtained with Spectral Analysis (SA) based on ROI data. ACG = anterior cingulate gyrus, IFG = inferior frontal gyrus, caudate = caudate nucleus, pallidum = globus pallidus, accumbens = nucleus accumbens. BS = between-subjects, CV = coefficient of variation, diff = difference, ICC = intraclass correlation coefficient, Min = minimum, Max = maximum, ROI = region-of-interest, SD = standard deviation.
| ROI | Median | Interquartile range | Min | Max | Median % diff | Median % diff range | Mean BS % CV | ICC |
|---|---|---|---|---|---|---|---|---|
| Hippocampus | 12.4 | 9.4–17.2 | 6.6 | 23.4 | 10.9 | − 39.3–29.6 | 34.1 | 0.87 |
| ACG | 14.4 | 11.9–19.9 | 7.3 | 27.1 | 12.4 | − 64.3–39.3 | 35.0 | 0.74 |
| IFG | 13.9 | 10.1–19.3 | 5.4 | 26.3 | 13.3 | − 76.3–47.3 | 39.0 | 0.71 |
| Caudate | 13.0 | 9.3–19.4 | 5.9 | 28.1 | 13.6 | − 80.8–26.3 | 44.2 | 0.74 |
| Pallidum | 15.7 | 12–21.7 | 8.2 | 28.9 | 9.4 | − 53.8–33.5 | 35.5 | 0.85 |
| Accumbens | 13.9 | 11.3–18.9 | 6.9 | 26.7 | 15.1 | − 63.6–47.1 | 35.2 | 0.80 |
| Thalamus | 9.6 | 6.9–12.2 | 4.8 | 20.3 | 24.7 | − 60.7–49.2 | 39.4 | 0.70 |
| Pons | 6.0 | 4.6–7.1 | 2.9 | 11.8 | 24.8 | − 62.0–39.9 | 35.5 | 0.67 |
| Mean (SD) |
15.5 (6.0) |
37.2 (3.4) |
0.76 (0.07) |