Table 3. Use of MCS While Listed for HTx Compared Between the 2 Eras.
Region Era 1/Era 2 (n) |
LVAD at HTx | p Value | RVAD at HTx | p Value | BiVAD at HTx | p Value | |||
---|---|---|---|---|---|---|---|---|---|
|
|
|
|||||||
Era 1 | Era 2 | Era 1 | Era 2 | Era 1 | Era 2 | ||||
Region 1 (316/427) | 18.4% (58) | 30.9% (132) | <0.001 | 0.6% (2) | 0.0% (0) | 0.100 | 6.6% (21) | 7.0% (30) | 0.839 |
Region 2 (1,077/1,475) | 14.1% (152) | 24.0% (354) | <0.001 | 0.7% (8) | 0.5% (8) | 0.526 | 2.7% (29) | 3.4% (50) | 0.315 |
Region 3 (1,010/1,273) | 6.8% (69) | 19.6% (250) | <0.001 | 0.1% (1) | 0.1% (1) | 0.870 | 2.0% (20) | 1.5% (19) | 0.372 |
Region 4 (819/964) | 6.6% (54) | 22.3% (215) | <0.001 | 0.2% (2) | 0.0% (0) | 0.125 | 1.2% (10) | 0.7% (7) | 0.284 |
Region 5 (1,264/1,567) | 4.4% (56) | 15.5% (243) | <0.001 | 0.3% (4) | 0.3% (4) | 0.760 | 2.5% (31) | 6.5% (102) | <0.001 |
Region 6 (284/278) | 13.0% (37) | 46.8% (130) | <0.001 | 0.0% (0) | 0.7% (2) | 0.152 | 3.5% (10) | 2.9% (8) | 0.665 |
Region 7 (860/939) | 14.1% (121) | 43.2% (406) | <0.001 | 0.1% (1) | 0.2% (2) | 0.616 | 1.6% (14) | 2.8% (26) | 0.101 |
Region 8 (406/616) | 12.3% (50) | 24.2% (149) | <0.001 | 0.0% (0) | 0.3% (2) | 0.250 | 0.5% (2) | 2.6% (16) | 0.012 |
Region 9 (752/638) | 13.0% (98) | 33.5% (214) | <0.001 | 0.0% (0) | 0.5% (3) | 0.060 | 3.1% (23) | 6.3% (40) | 0.004 |
Region 10 (845/832) | 16.2% (137) | 36.9% (307) | <0.001 | 0.5% (4) | 0.1% (1) | 0.184 | 1.5% (13) | 4.0% (33) | 0.002 |
Region 11 (945/1,129) | 12.6% (119) | 26.3% (297) | <0.001 | 0.1% (1) | 0.2% (2) | 0.670 | 1.8% (17) | 2.5% (28) | 0.289 |
All (8,578/10,138)* | 11.1% (951) | 26.6% (2697) | <0.001 | 0.3% (23) | 0.2% (25) | 0.771 | 2.2% (190) | 3.5% (359) | <0.001 |
| |||||||||
Region Era 1/Era 2 (n) |
TAH at HTx | p Value | MCS all at HTx | p Value | |||||
|
|
||||||||
Era 1 | Era 2 | Era 1 | Era 2 | ||||||
| |||||||||
Region 1 (316/427) | 0.0% (0) | 0.0% (0) | NA | 25.6% (81) | 37.9% (162) | <0.001 | |||
Region 2 (1,077/1,475) | 0.0% (0) | 0.7% (10) | 0.007 | 17.5% (189) | 28.6% (422) | <0.001 | |||
Region 3 (1,010/1,273) | 0.0% (0) | 0.0% (0) | NA | 8.9% (90) | 21.2% (270) | <0.001 | |||
Region 4 (819/964) | 0.0% (0) | 0.5% (5) | 0.039 | 8.1% (66) | 23.5% (227) | <0.001 | |||
Region 5 (1,264/1,567) | 0.7% (9) | 2.2% (35) | 0.001 | 7.9% (100) | 24.5% (384) | <0.001 | |||
Region 6 (284/278) | 0.0% (0) | 0.0% (0) | NA | 16.5% (47) | 50.4% (140) | <0.001 | |||
Region 7 (860/939) | 0.1% (1) | 0.3% (3) | 0.361 | 15.9% (137) | 46.4% (436) | <0.001 | |||
Region 8 (406/616) | 0.0% (0) | 0.2% (1) | 0.417 | 12.8% (52) | 27.3% (168) | <0.001 | |||
Region 9 (752/638) | 0.0% (0) | 0.2% (1) | 0.277 | 16.1% (121) | 40.4% (258) | <0.001 | |||
Region 10 (845/832) | 0.5% (4) | 1.7% (14) | 0.016 | 18.7% (158) | 42.6% (355) | <0.001 | |||
Region 11 (945/1,129) | 0.1% (1) | 4.1% (46) | <0.001 | 14.6% (138) | 33.0% (373) | <0.001 | |||
All (8,578/10,139)* | 0.2% (15) | 1.1% (115) | <0.001 | 13.7% (1179) | 31.5% (3195) | <0.001 |
Use of mechanical circulatory support (MCS) while listed for heart transplantation (HTx) compared between the 2 eras (percent of patients and absolute numbers listed; Era 1: January 20, 1999 to July 11, 2006; Era 2: July 12, 2006 to April 30, 2012).
Data of 4,674 patients in Era 1 and that of 1 patient in Era 2 not obtained.
BiVAD = bi-ventricular assist device; LVAD = left ventricular assist device; RVAD = right ventricular assist device; TAH = total artificial heart.