Table 1.
Baseline Characteristics
| Regular List (n=711) | High-Risk List (n=111) | P Value | |
|---|---|---|---|
| Clinical characteristics at the time of cardiac transplantation | |||
| Age, y | 51.4±11.8 | 63.2±10.2 | <0.001 |
| Sex (male), % | 549 (77.2) | 86 (77) | 0.841 |
| Race (white), % | 434 (61.0) | 73 (66) | 0.892 |
| BMI, kg/m2 | 25.7±4.8 | 25.9±5.2 | 0.660 |
| Prior LVAD, % | 234 (32.9) | 27 (24.3) | 0.071 |
| Ejection fraction, % | 18±9 | 20±9 | 0.06 |
| Coronary artery disease, % | 305 (42.9) | 52 (46.9) | 0.438 |
| Prior myocardial infarction, % | 143 (20.1) | 32 (28.8) | 0.038 |
| Cerebral vascular accident, % | 82 (11.5) | 15 (13.5) | 0.546 |
| Peripheral vascular disease, % | 35 (4.9) | 8 (7.2) | 0.317 |
| Diabetes mellitus, % | 194 (27.3) | 38 (34.2) | 0.133 |
| Hypertension, % | 270 (38.0) | 50 (45.0) | 0.135 |
| Prior smoker, % | 239(34) | 41 (37.3) | 0.508 |
| Prior cancer, % | 39 (6.03) | 11 (11.6) | 0.044 |
| COPD, % | 21 (3.3) | 5 (4.9) | 0.410 |
| Preoperative laboratory values | |||
| Albumin, mg/dL | 4.0±2.2 | 3.9±0.6 | 0.459 |
| Sodium, mEq/L | 135±4 | 136±3 | 0.288 |
| Potassium, mEq/L | 4.3±0.5 | 4.5±0.5 | 0.149 |
| BUN, mg/dL | 28±15 | 34±18 | <0.001 |
| Creatinine, mg/dL | 1.4±0.8 | 1.5±0.5 | 0.407 |
| GFR–MDRD, mL/min | 68±30 | 57±23 | <0.001 |
| Total bilirubin, mg/dL | 1.2±1.1 | 1.1±0.9 | 0.520 |
| Direct bilirubin, mg/dL | 0.3±0.5 | 0.3±0.4 | 0.660 |
| AST, IU/L | 35±63 | 31±19 | 0.473 |
| ALT, IU/L | 36±76 | 27±22 | 0.227 |
| Total cholesterol, mg/dL | 151±46 | 153±45 | 0.567 |
| Triglyceride, mg/dL | 122±79 | 127±75 | 0.580 |
| Hematocrit, % | 36.1±6.2 | 37.2±5.7 | 0.080 |
| Hemoglobin, g/dL | 11.9±4.2 | 12.1±2.0 | 0.600 |
| Platelet count | 235±86 | 215±72 | 0.030 |
| Perioperative and donor-related information | |||
| Donor age, y | 33.0±13.0 | 40.9±13.6 | <0.001 |
| Donor ischemic time, min | 191±73 | 201±52 | 0.210 |
| Cardiopulmonary bypass time, min | 163±46 | 166±53 | 0.493 |
| Aortic cross-clamp time, min | 97±29 | 96±24 | 0.836 |
| Mean survival, d | 2937±60 | 2238±157 | 0.001 |
ALT indicates alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; COPD, chronic obstructive pulmonary disease; GFR, glomerular filtration rate; LVAD, left ventricular assist device; and MDRD, modification of diet in renal disease.