Table 3.
Comparison of metabolic and comorbid data between patients with postglucose GH nadir over (group A) and below 0.4 μg/L (group B) at last follow-up.
| Parameter | Group A | Group B | P |
|---|---|---|---|
| (GH-n ≥ 0.4 mcg/L) | (GH-n < 0.4 mcg/L) | ||
| n | 11 | 29 | — |
| BMI (Kg/m2) | 24.4 ± 4.6 | 28.6 ± 4.4 | ns |
| Impaired glucose metabolism (y/n) | 4/7 | 13/16 | ns |
| IFG, IGT, DM (n) | 1/2/1 | 0/9/4 | |
| Fasting glucose (mg/dL) | 85 ± 14 | 97 ± 20 | ns |
| Glucose at 120′ (mg/dL) | 138 ± 57 | 128 ± 36 | ns |
| HOMA-IR | 2.0 ± 1.7 | 2.1 ± 1.8 | ns |
| Blood hypertension (y/n) | 3/8 | 12/17 | ns |
| SBP (mmHg) | 115 ± 15 | 122 ± 12 | ns |
| DBP (mmHg) | 74 ± 11 | 79 ± 7 | ns |
| Cardio- and/or cerebrovascular disease (y/n) | 6/5 | 10/19 | ns |
| Valvular heart disease | 4 | 4 | |
| Acromegalic cardiomyopathy | 1 | 1 | |
| Arrhythmias and cardiomyopathy | 0 | 5 | |
| Acute myocardial infarction | 1 | 0 | |
| Malignancies (y/n) | 3/8 | 2/27 | ns |
| Mammary carcinoma | 1 | 0 | |
| Monoclonal gammopathy | 2 | 0 | |
| Olfactory meningioma | 0 | 1 | |
| Skin melanoma | 0 | 1 | |
| Colorectal disease | 2/9 | 7/22 | ns |
| Diverticula | 0 | 3 | |
| Dolichocolon | 0 | 1 | |
| Hyperplastic polyps | 0 | 2 | |
| Adenomatous polyps | 2* | 1° |
IFG: impaired fasting glucose; IGT: impaired glucose tolerance; DM: diabetes mellitus; NS: not significant.
*Low grade adenomatous tubular polyps, °serrated adenoma with low grade dysplasia.