Table 1.

Tumor formation in immunocompromised mice

BJT/p53/p16KD/ST +	No. of tumors/No. of injected
	6.5 weeks	9 weeks
YAPS127A	6/6	Culled
RasV12	6/6	Culled
shLats2 no. 1	0/6	3/6
shSOCS6 no. 2	0/6	4/6
Control	0/4	0/4

BJ^{T/p53KD/p16KD/ST} cells, lacking Ras^V12, were retrovirally transduced to express the indicated transgenes or with an empty vector as a control. Cells were injected subcutaneously in immunocompromised NOD-scid Il2rg^−/− mice (Chen et al, 2009).

Tumors are shown in Supplementary Fig S2.