Table 1.
Wild types and fluoroquinolone-resistant mutants of C. perfringens used in this study with stable mutations in gyrA and parC resulting in amino acid conversion.
|
C. perfringens
strain |
Wild type | Norfloxacin-resistantNR | Ciprofloxacin-resistantCR | Gatifloxacin-resistantGR |
|---|---|---|---|---|
| VPI | — | D87Y gyrA, V196F parC | D87Y gyrA, D87Y parC | G81C gyrA, D93Y and D502Y parC |
| NCTR | — | D87Y gyrA | D87Y gyrA | G81C and D87Y gyrA |
| 3626 | — | G81C gyrA, D87Y parC | D87Y gyrA, D93Y parC | G81C and D87Y gyrA, D93Y and A131S parC |
| 13124 | — | A119E | D87Y gyrA, S89I gyrA | G81C and D93Y gyrA, S89I parC |